A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of keratoconus
ncRNA name MEG3
ncRNA Category lncRNA
ID 55384
Ensembl ENSG00000214548
Synonyms GTL2; FP504; prebp1; PRO0518; PRO2160; LINC00023; NCRNA00023; onco-lncRNA-83
Disease name keratoconus
Species Homo sapiens
Tissues/Cell_line corneas
Methods RNA-Seq, ddPCR
Expression pattern down-regulated
Functional description Using |fold change| ≥ 2 and a false discovery rate ≤ 0.05, we identified 436 coding RNAs and 584 lncRNAs with differential expression in the KC-affected corneas. We selected seven differentially expressed lncRNAs for ddPCR validation. Five lncRNA showed a similar trend to RNA-Seq results.
PubMed ID 29860458
Year 2018
Title Differential Expression of Coding and Long Noncoding RNAs in Keratoconus-Affected Corneas.
Drug-related ncRNA NO

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