A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of herpes simplex virus keratitis
ncRNA name ICP4 siRNA
ncRNA Category siRNA
Disease name herpes simplex virus keratitis
Species Mus musculus
Tissues/Cell_line corneas
Methods siRNA instillation, fluorescence, RT-PCR
Expression pattern associated
Functional description In mouse HSK, the application of ICP4-siRNA+PEI eye drops reduced the damage to the corneal epithelia and decreased viral VP16 expression in the corneal tissue.
PubMed ID 25336327
Year 2014
Title A new approach of delivering siRNA to the cornea and its application for inhibiting herpes simplex keratitis.
Drug-related ncRNA NO

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