A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name hsa-miR-200b
ncRNA Category miRNA
Disease name glaucoma
Species Homo sapiens
Tissues/Cell_line human Tenon's fibroblasts (HTFs)
Methods Western blot, immunofluorescence, qPCR, transfection, luciferase reporter assay
Expression pattern up-regulated
Functional description TGF-β1-mediated miR-200b induces HTFs fibrosis through suppressing PTEN signaling pathway.
PubMed ID 30512998
Year 2018
Title TGF-β1 Induces Human Tenon's Fibroblasts Fibrosis via miR-200b and Its Suppression of PTEN Signaling.
Drug-related ncRNA NO

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