ncRNA name | CTGF siRNA |
ncRNA Category | siRNA |
Disease name | glaucoma |
Species | Oryctolagus cuniculus |
Tissues/Cell_line | primary tenon cells; rabbit eyes |
Methods | siRNA transfection, Viral transduction, Western blot, immunocytochemistry, immunohistochemistry |
Expression pattern | associated |
Functional description | Down-regulation of CTGF is effective in inhibiting postoperative scarring in vivo. This suggests that RNAi with CTGF siRNA may potentially pave the road for a novel therapeutic strategy to improve glaucoma surgery results. |
PubMed ID | 26554857 |
Year | 2016 |
Title | Evaluation of Adenovirus-Mediated Down-Regulation of Connective Tissue Growth Factor on Postoperative Wound Healing After Experimental Glaucoma Surgery. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.