A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name mmu-miR-200a
ncRNA Category miRNA
Disease name glaucoma
Species Mus musculus
Tissues/Cell_line retinas
Methods luciferase reporter assay, immunohistochemistry, MTT assay, TUNEL assay, qRT-PCR, Western blot
Expression pattern down-regulated
Functional description miR-200a can inhibit the FGF7-mediated MAPK signaling pathway and play a protective role on improving the glaucoma-induced optical nerve injury.
PubMed ID 30439502
Year 2019
Title Neuroprotective effects of overexpressed microRNA-200a on activation of glaucoma-related retinal glial cells and apoptosis of ganglion cells via downregulating FGF7-mediated MAPK signaling pathway.
Drug-related ncRNA NO

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