ncRNA name | mmu-miR-200a |
ncRNA Category | miRNA |
Disease name | glaucoma |
Species | Mus musculus |
Tissues/Cell_line | retinas |
Methods | luciferase reporter assay, immunohistochemistry, MTT assay, TUNEL assay, qRT-PCR, Western blot |
Expression pattern | down-regulated |
Functional description | miR-200a can inhibit the FGF7-mediated MAPK signaling pathway and play a protective role on improving the glaucoma-induced optical nerve injury. |
PubMed ID | 30439502 |
Year | 2019 |
Title | Neuroprotective effects of overexpressed microRNA-200a on activation of glaucoma-related retinal glial cells and apoptosis of ganglion cells via downregulating FGF7-mediated MAPK signaling pathway. |
Drug-related ncRNA | NO |
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