ncRNA name | mmu-miR-149 |
ncRNA Category | miRNA |
Disease name | glaucoma |
Species | Mus musculus |
Tissues/Cell_line | retinas |
Methods | H&E staining, TUNEL assay, transfection, luciferase reporter assay, qRT-PCR, Western blot, CCK-8 assay, Annexin V-FITC/PI assay |
Expression pattern | associated |
Functional description | The downregulation of miR-149 confers protection to RGCs by means of activating the PI3K/Akt signaling pathway via upregulation of BTC in mice with glaucoma. |
PubMed ID | 30183321 |
Year | 2018 |
Title | Downregulation of microRNA-149 in retinal ganglion cells suppresses apoptosis through activation of the PI3K/Akt signaling pathway in mice with glaucoma. |
Drug-related ncRNA | NO |
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