A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name mmu-miR-187
ncRNA Category miRNA
Disease name glaucoma
Species Mus musculus
Tissues/Cell_line retinal ganglion cell line RGC-5
Methods CCK-8 assay, flow cytometry, Western blot, qRT-PCR, transfection, luciferase reporter assay
Expression pattern down-regulated
Functional description We confirmed that the forced miR-187 expression alleviated oxidative stress injury in retina tissues of rat models with chronic ocular hypertension.
PubMed ID 30170060
Year 2018
Title Down-regulated miR-187 promotes oxidative stress-induced retinal cell apoptosis through P2X7 receptor.
Drug-related ncRNA NO

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