A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name hsa-miR-181a
ncRNA Category miRNA
Disease name glaucoma
Species Homo sapiens
Tissues/Cell_line trabecular meshwork cells
Methods qRT-PCR, MTT assay, apoptosis assay, Western blot
Expression pattern down-regulated
Functional description miR-181a could improve the survival rate of TM cells after H2O2 treatment by blocking the NF-κB and JNK signaling pathways.
PubMed ID 29616751
Year 2018
Title MiR-181a inhibits human trabecular meshwork cell apoptosis induced by H₂O₂ through the suppression of NF-κB and JNK pathways.
Drug-related ncRNA NO

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