A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name hsa-miR-1298
ncRNA Category miRNA
Disease name glaucoma
Species Homo sapiens
Tissues/Cell_line human trabecular meshwork (HTM) cells
Methods qRT-PCR, transfection, luciferase reporter assay, flow cytometry, Western blot
Expression pattern down-regulated
Functional description miR-1298 could protect HTM cells to against damage caused by COS via inhibiting TGF-β2/Smad4 pathway and activating canonical Wnt pathway.
PubMed ID 29453044
Year 2018
Title Micro RNA-1298 opposes the effects of chronic oxidative stress on human trabecular meshwork cells via targeting on EIF4E3.
Drug-related ncRNA NO

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