ncRNA name | hsa-miR-1298 |
ncRNA Category | miRNA |
Disease name | glaucoma |
Species | Homo sapiens |
Tissues/Cell_line | human trabecular meshwork (HTM) cells |
Methods | qRT-PCR, transfection, luciferase reporter assay, flow cytometry, Western blot |
Expression pattern | down-regulated |
Functional description | miR-1298 could protect HTM cells to against damage caused by COS via inhibiting TGF-β2/Smad4 pathway and activating canonical Wnt pathway. |
PubMed ID | 29453044 |
Year | 2018 |
Title | Micro RNA-1298 opposes the effects of chronic oxidative stress on human trabecular meshwork cells via targeting on EIF4E3. |
Drug-related ncRNA | NO |
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