A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name rno-miR-124
ncRNA Category miRNA
Disease name glaucoma
Species Rattus norvegicus
Tissues/Cell_line retinas
Methods luciferase reporter assay, immunocytochemical and Edu labeling, RT-PCR, Western blot, TUNEL assay
Expression pattern associated
Functional description In rat chronic ocular hypertension glaucoma model, miR-124 promoted axon growth of RGCs differentiated from retinal stem cells. Furthermore, we found that miR-124 negatively regulated CoREST via directly targeting the binding site in CoREST 3' UTR.
PubMed ID 29428935
Year 2018
Title MiR-124 Promotes the Growth of Retinal Ganglion Cells Derived from Müller Cells.
Drug-related ncRNA NO

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