ncRNA name | mmu-miR-124 |
ncRNA Category | miRNA |
Disease name | glaucoma |
Species | Mus musculus |
Tissues/Cell_line | retinal ganglion cell line RGC-5 |
Methods | luciferase reporter assay, immunocytochemical and Edu labeling, RT-PCR, Western blot, TUNEL assay |
Expression pattern | associated |
Functional description | In rat chronic ocular hypertension glaucoma model, miR-124 promoted axon growth of RGCs differentiated from retinal stem cells. Furthermore, we found that miR-124 negatively regulated CoREST via directly targeting the binding site in CoREST 3' UTR. |
PubMed ID | 29428935 |
Year | 2018 |
Title | MiR-124 Promotes the Growth of Retinal Ganglion Cells Derived from Müller Cells. |
Drug-related ncRNA | NO |
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