ncRNA name | hsa-miR-26a |
ncRNA Category | miRNA |
Disease name | glaucoma |
Species | Homo sapiens |
Tissues/Cell_line | scar samples and subconjunctival Tenon’s capsule tissues |
Methods | qRT-PCR, cell migration assay, luciferase reporter assay, Western blot |
Expression pattern | associated |
Functional description | It was found that miR-26a was significantly down-regulated in filtering tract scar.The key finding of the current study is that miR-26a can suppress the activation of HTFs by transforming growth factor (TGF)-β by targeting CTGF. This data indicates that miR-26a plays an essential role in the formation of filtering tract scar and function as a potential drug target. |
PubMed ID | 28685590 |
Year | 2018 |
Title | A key role of microRNA-26a in the scar formation after glaucoma filtration surgery. |
Drug-related ncRNA | NO |
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