| ncRNA name | ADAR2 siRNA |
| ncRNA Category | siRNA |
| Disease name | glaucoma |
| Species | Rattus norvegicus |
| Tissues/Cell_line | retinal ganglion cells (RGCs) |
| Methods | qRT-PCR, Western blot, immunohistochemistry, TUNEL assay, siRNA transfection, immunocytochemistry |
| Expression pattern | associated |
| Functional description | Knockdown of ADAR2 using siRNA increased the accumulation of Co(2+) in response to glutamate, and decreased the rectification index of AMPA currents detected electrophysiologically, indicating an increased Ca(2+) permeability through AMPARs. |
| PubMed ID | 24608178 |
| Year | 2014 |
| Title | Down-regulation of the RNA editing enzyme ADAR2 contributes to RGC death in a mouse model of glaucoma. |
| Drug-related ncRNA | NO |
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