A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name Akt siRNA
ncRNA Category siRNA
Disease name glaucoma
Species Homo sapiens
Tissues/Cell_line human subconjunctival fibroblasts
Methods siRNA transfection, Western blot, MTT assay, immunocytochemistry
Expression pattern associated
Functional description TGF-β1-induced α-SMA expression was significantly decreased by LY294002 and Akt siRNA.
PubMed ID 24563318
Year 2014
Title Lithium chloride inhibits TGF-β1-induced myofibroblast transdifferentiation via PI3K/Akt pathway in cultured fibroblasts from Tenon's capsule of the human eye.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.