A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name CTGF siRNA
ncRNA Category siRNA
Disease name glaucoma
Species Homo sapiens
Tissues/Cell_line human Tenon capsule fibroblasts (HTFs)
Methods siRNA transfection, qRT-PCR, immunocytochemistry, CCK-8 assay, flow cytometry
Expression pattern associated
Functional description CTGF targeting siRNA could effectively suppress the expression of CTGF and attenuate the proliferation of HTFs.
PubMed ID 24288593
Year 2013
Title RNA Interference Targeting Connective Tissue Growth Factor Inhibits the Transforming Growth Factor- β 2 Induced Proliferation in Human Tenon Capsule Fibroblasts.
Drug-related ncRNA NO

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