ncRNA name | SYL040012 |
ncRNA Category | siRNA |
Disease name | glaucoma |
Species | Oryctolagus cuniculus |
Tissues/Cell_line | ciliary bodies, lachrymal glands, corneas; rabbit fibroblast cell line RAB-9 |
Methods | siRNA transfection, qPCR, MTT assay |
Expression pattern | associated |
Functional description | SYL040012 reduces IOP in normotensive and hypertensive animal models and the effect appears to be long lasting and extremely well tolerated both locally and systemically. |
PubMed ID | 24025749 |
Year | 2014 |
Title | In vitro and in vivo efficacy of SYL040012, a novel siRNA compound for treatment of glaucoma. |
Drug-related ncRNA | NO |
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