A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name mmu-miR-187
ncRNA Category miRNA
Disease name glaucoma
Species Mus musculus
Tissues/Cell_line retinal ganglion cell line RGC-5
Methods transfection, flow cytometry, CCK-8 assay, Western blot
Expression pattern associated
Functional description miR-187 negatively regulated cell survival via inhibiting cell apoptosis and promoting cell proliferation through upregulating SMAD7. It plays a vital role in retinal ganglion cell survival.
PubMed ID 26463627
Year 2015
Title Decreased miR-187 induces retinal ganglion cell apoptosis through upregulating SMAD7 in glaucoma.
Drug-related ncRNA NO

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