ncRNA name | P2Y(2) siRNA |
ncRNA Category | siRNA |
Disease name | glaucoma |
Species | Oryctolagus cuniculus |
Tissues/Cell_line | ciliary process samples |
Methods | siRNA instillation, RT-PCR, qPCR, Western blot, immunohistochemistry |
Expression pattern | associated |
Functional description | P2Y(2) receptors increase IOP in New Zealand rabbits. The application of a siRNA for this receptor significantly reduced IOP, suggesting that this technology might be used for the treatment of glaucoma. |
PubMed ID | 21740413 |
Year | 2012 |
Title | Silencing of P2Y(2) receptors reduces intraocular pressure in New Zealand rabbits. |
Drug-related ncRNA | NO |
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