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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name IKKβ siRNA
ncRNA Category siRNA
Disease name glaucoma
Species Macaca mulatta
Tissues/Cell_line Tenon’s fibroblasts; monkey eyes
Methods siRNA transfection and injection, qRT–PCR, Western blot, cell proliferation assay, histologic analysis
Expression pattern associated
Functional description Subconjunctival injection of cationic nano-copolymers mediated IKKβ targeting siRNA is associated with improved surgical outcome in a monkey model of trabeculectomy.
PubMed ID 21139997
Year 2010
Title Cationic nano-copolymers mediated IKKβ targeting siRNA to modulate wound healing in a monkey model of glaucoma filtration surgery.
Drug-related ncRNA NO

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