A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name hsa-miR-200b
ncRNA Category miRNA
Disease name glaucoma
Species Homo sapiens
Tissues/Cell_line human Tenon's capsule fibroblasts (HTFs)
Methods immunofluorescence, CCK-8 assay, EdU assay, Western blot, qRT-PCR, transfection, luciferase reporter assay
Expression pattern up-regulated
Functional description MicroRNA-200b acts as a stimulant for the proliferation of HTFs by targeting p27/kip1 and RND3.
PubMed ID 24667864
Year 2014
Title TGF-β1 stimulates human Tenon's capsule fibroblast proliferation by miR-200b and its targeting of p27/kip1 and RND3.
Drug-related ncRNA NO

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