| ncRNA name | TGFβR2 siRNA |
| ncRNA Category | siRNA |
| Disease name | glaucoma |
| Species | Homo sapiens |
| Tissues/Cell_line | human optic nerve head astrocytes |
| Methods | qRT-PCR, Western blot, siRNA transfection, immunofluorescence |
| Expression pattern | associated |
| Functional description | The authors investigated the role of myosin light chain kinase (MYLK) and transforming growth factor beta (TGFbeta) receptor pathways in optic nerve head (ONH) astrocyte migration. SiRNA directed against TGFbeta receptor 2 decreased cell migration compared with control and decreased extracellular matrix genes regulated by TGFbeta signaling. |
| PubMed ID | 20375339 |
| Year | 2010 |
| Title | Modulation of factors affecting optic nerve head astrocyte migration. |
| Drug-related ncRNA | NO |
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