ncRNA name | MYLK siRNA |
ncRNA Category | siRNA |
Disease name | glaucoma |
Species | Homo sapiens |
Tissues/Cell_line | human optic nerve head astrocytes |
Methods | qRT-PCR, Western blot, siRNA transfection, immunofluorescence |
Expression pattern | associated |
Functional description | The authors investigated the role of myosin light chain kinase (MYLK) and transforming growth factor beta (TGFbeta) receptor pathways in optic nerve head (ONH) astrocyte migration. MYLK-directed siRNA decreased MYLK expression and cell migration compared with control siRNA. |
PubMed ID | 20375339 |
Year | 2010 |
Title | Modulation of factors affecting optic nerve head astrocyte migration. |
Drug-related ncRNA | NO |
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