| ncRNA name | hsa-miR-204 |
| ncRNA Category | miRNA |
| Disease name | glaucoma |
| Species | Homo sapiens |
| Tissues/Cell_line | human trabecular meshwork cells (HTM) |
| Methods | microarray, immunoblot, transfection, luciferase reporter assay |
| Expression pattern | associated |
| Functional description | FOXC1 is implicated in the etiology of glaucoma because mutations in the gene are among the causes of Axenfeld-Rieger syndrome which is often accompanied by glaucoma. It was observed that miR-204 caused decreased expression of FOXC1 and the FOXC1 target genes CLOCK, PLEKHG5, ITGβ1, and MEIS2 in the TM cultures. |
| PubMed ID | 23541832 |
| Year | 2013 |
| Title | FOXC1 in human trabecular meshwork cells is involved in regulatory pathway that includes miR-204, MEIS2, and ITGβ1. |
| Drug-related ncRNA | NO |
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