| ncRNA name | hsa-miR-24 |
| ncRNA Category | miRNA |
| Disease name | glaucoma |
| Species | Homo sapiens |
| Tissues/Cell_line | human trabecular meshwork cells (HTM) |
| Methods | transfection, qPCR, microarray, Western blot |
| Expression pattern | associated |
| Functional description | Cyclic mechanical stress (CMS) leads to alterations of cellular functions in the trabecular meshwork (TM), including the up-regulation of transforming growth factor beta 1 (TGFβ1), that can potentially contribute to the pathogenesis of glaucoma. miR-24 might play an important role in modulating the induction of TGFβ1 mediated by CMS through direct targeting of FURIN. |
| PubMed ID | 20945401 |
| Year | 2011 |
| Title | MicroRNA-24 regulates the processing of latent TGFβ1 during cyclic mechanical stress in human trabecular meshwork cells through direct targeting of FURIN. |
| Drug-related ncRNA | NO |
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