A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name cochlin shRNA
ncRNA Category shRNA
Disease name glaucoma
Species Mus musculus
Tissues/Cell_line trabecular meshwork
Methods Western blot, shRNA knockdown, PCR, immunohistochemistry, SDOCT
Expression pattern associated
Functional description Mice injected with cochlin shRNA at six months of age showed a decrease in IOP and maintained the decreased IOP level for the next two months compared to control injected eyes.
PubMed ID 22496787
Year 2012
Title Cochlin, intraocular pressure regulation and mechanosensing.
Drug-related ncRNA NA

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