| ncRNA name | VEGF shRNA |
| ncRNA Category | shRNA |
| Disease name | glaucoma |
| Species | Homo sapiens |
| Tissues/Cell_line | human Tenon's capsule fibroblasts (HTFs) |
| Methods | shRNA knockdown, qRT-PCR, Western blot, proliferation assay |
| Expression pattern | associated |
| Functional description | Both mRNA and protein levels of VEGF were reduced by lentivirus-mediated VEGF-shRNA, and proliferation of HTF cells was inhibited. VEGF may be a suitable therapeutic target for reducing scar tissue formation in glaucoma patients after filtration surgery. |
| PubMed ID | 28168047 |
| Year | 2017 |
| Title | Suppression of Human Tenon Fibroblast Cell Proliferation by Lentivirus-Mediated VEGF Small Hairpin RNA. |
| Drug-related ncRNA | NA |
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