ncRNA name | Gas5 |
ncRNA Category | lncRNA |
ID | 14455 |
Ensembl | ENSMUSG00000053332 |
Synonyms | Gas-5; Snhg2; Mir5117 |
Disease name | glaucoma |
Species | Mus musculus |
Tissues/Cell_line | retinal ganglion cell line RGC-5 |
Methods | siRNA transfection, qRT-PCR, CCK-8 assay, flow cytometry |
Expression pattern | associated |
Functional description | Down-regulation of lncRNA GAS5 may maintain retinal ganglion cell survival in glaucoma through the activation of TGF-β pathway to promote cell proliferation and differentiation. |
PubMed ID | 29509235 |
Year | 2018 |
Title | Long non-coding RNA GAS5 contributed to the development of glaucoma via regulating the TGF-β signaling pathway. |
Drug-related ncRNA | NO |
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