A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name Gas5
ncRNA Category lncRNA
ID 14455
Ensembl ENSMUSG00000053332
Synonyms Gas-5; Snhg2; Mir5117
Disease name glaucoma
Species Mus musculus
Tissues/Cell_line retinal ganglion cell line RGC-5
Methods siRNA transfection, qRT-PCR, CCK-8 assay, flow cytometry
Expression pattern associated
Functional description Down-regulation of lncRNA GAS5 may maintain retinal ganglion cell survival in glaucoma through the activation of TGF-β pathway to promote cell proliferation and differentiation.
PubMed ID 29509235
Year 2018
Title Long non-coding RNA GAS5 contributed to the development of glaucoma via regulating the TGF-β signaling pathway.
Drug-related ncRNA NO

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