A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name Malat1
ncRNA Category lncRNA
Ensembl NA
Synonyms NA
Disease name glaucoma
Species Rattus norvegicus
Tissues/Cell_line retinal ganglion cells
Methods qRT-PCR, Western blot, flow cytometry, immunohistochemistry, TUNEL assay
Expression pattern down-regulated
Functional description Our study provides evidence that LncRNA-MALAT1 could inhibit RGC apoptosis in glaucoma through activation of the PI3K/Akt signaling pathway.
PubMed ID 29065394
Year 2017
Title Long Non-Coding RNA-MALAT1 Mediates Retinal Ganglion Cell Apoptosis Through the PI3K/Akt Signaling Pathway in Rats with Glaucoma.
Drug-related ncRNA NO

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