ncRNA name | A2AR siRNA |
ncRNA Category | siRNA |
Disease name | glaucoma |
Species | Mus musculus |
Tissues/Cell_line | mouse microglia cell line BV-2 |
Methods | siRNA transfection, phagocytosis assay, scratch wound assay, Boyden chamber migration assay, qPCR |
Expression pattern | associated |
Functional description | The A2A R antagonist SCH 58261 or the knockdown of A2A R expression with siRNA in microglial cells prevented the increase in microglia response to elevated hydrostatic pressure. |
PubMed ID | 30667095 |
Year | 2019 |
Title | Blockade of microglial adenosine A2A receptor suppresses elevated pressure-induced inflammation, oxidative stress, and cell death in retinal cells. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.