A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of glaucoma
ncRNA name MRTF-B siRNA
ncRNA Category siRNA
Disease name glaucoma
Species Oryctolagus cuniculus
Tissues/Cell_line conjunctival tissues
Methods siRNA injection, histological analysis
Expression pattern associated
Functional description In vivo, subconjunctival administration of LYR nanoparticles containing MRTF-B siRNAs doubled bleb survival in a pre-clinical rabbit model of glaucoma filtration surgery.
PubMed ID 30301666
Year 2018
Title Development of Targeted siRNA Nanocomplexes to Prevent Fibrosis in Experimental Glaucoma Filtration Surgery.
Drug-related ncRNA NO

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