ncRNA name | MRTF-B siRNA |
ncRNA Category | siRNA |
Disease name | glaucoma |
Species | Oryctolagus cuniculus |
Tissues/Cell_line | conjunctival tissues |
Methods | siRNA injection, histological analysis |
Expression pattern | associated |
Functional description | In vivo, subconjunctival administration of LYR nanoparticles containing MRTF-B siRNAs doubled bleb survival in a pre-clinical rabbit model of glaucoma filtration surgery. |
PubMed ID | 30301666 |
Year | 2018 |
Title | Development of Targeted siRNA Nanocomplexes to Prevent Fibrosis in Experimental Glaucoma Filtration Surgery. |
Drug-related ncRNA | NO |
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