ncRNA name | hsa-miR-511-5p |
ncRNA Category | miRNA |
Disease name | fungal keratitis |
Species | Homo sapiens |
Tissues/Cell_line | corneas |
Methods | RNA-seq, qRT-PCR |
Expression pattern | up-regulated |
Functional description | By deep sequencing, 75 miRNAs were identified as differentially expressed in fungal keratitis corneas. Based on high DE (≥6-fold) and functional relevance to corneal diseases, 16 miRNAs were selected for further validation by qPCR. The highly dysregulated miRNAs (miR-511-5p, miR-142-3p, miR-155-5p, and miR-451a) may regulate wound healing as they were predicted to specifically target wound inflammatory genes. |
PubMed ID | 26720440 |
Year | 2015 |
Title | Human Corneal MicroRNA Expression Profile in Fungal Keratitis. |
Drug-related ncRNA | NO |
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