A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of fungal keratitis
ncRNA name TLR2 siRNA
ncRNA Category siRNA
Disease name fungal keratitis
Species Rattus norvegicus
Tissues/Cell_line corneas
Methods siRNA injection, immunofluorescence assay, Histopathological examinations, Periodic acid Schiff staining, PMN infiltration, qPCR
Expression pattern associated
Functional description TLR2 siRNA treatment attenuated A. fumigatus keratitis by suppressing corneal inflammation and preventing fungal invasion.
PubMed ID 21647173
Year 2012
Title Toll-like receptor 2 siRNA suppresses corneal inflammation and attenuates Aspergillus fumigatus keratitis in rats.
Drug-related ncRNA NO

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