ncRNA name | TLR2 siRNA |
ncRNA Category | siRNA |
Disease name | fungal keratitis |
Species | Homo sapiens |
Tissues/Cell_line | telomerase-immortalized human corneal epithelial cells (THCEs) |
Methods | siRNA transfection, RT-PCR, Western blot, ELISA |
Expression pattern | associated |
Functional description | Treatment with TLR2- or TLR4-siRNA plasmid reduced TLR2 or TLR4 expression level in THCE when compared with controls, and caused a significant decrease in A. fumigatus-induced IL-1beta and IL-6 production. |
PubMed ID | 19341426 |
Year | 2009 |
Title | Innate responses of corneal epithelial cells against Aspergillus fumigatus challenge. |
Drug-related ncRNA | NO |
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