|telomerase-immortalized human stroma fibroblasts (THSF)
|siRNA transfection, immunofluorescence analysis, RT-PCR, Western blot, qPCR
|THSF transfected with TLR2-siRNA plasmid exhibited a reduced level of TLR2 when compared with the control cells transfected with empty plasmid. F. solu-stimulated IL-10 production by transfected THSF was severely impaired, while IL-1beta production was partially inhibited.
|Toll-like receptor 2 mediates the induction of IL-10 in corneal fibroblasts in response to Fusarium solu.
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