A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name MMP-9 siRNA
ncRNA Category siRNA
Disease name diabetic retinopathy (DR)
Species Rattus norvegicus
Tissues/Cell_line retinal Müller cells (RMCs)
Methods siRNA transfection, flow cytometry, MTT assay, qRT-PCR, Western blot
Expression pattern associated
Functional description The cell viability of siRNA-MMP9 group was significantly increased while decreased in MMP9 overexpression group when compared to control group, respectively. The apoptotic cells in MMP9 overexpression group significantly increased while decreased in siRNA-MMP9 group when compared with control group.
PubMed ID 26617754
Year 2015
Title Apoptotic effect of mtrix metalloproteinases 9 in the development of diabetic retinopathy.
Drug-related ncRNA NO

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