A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name mmu-miR-29b
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Mus musculus
Tissues/Cell_line mouse Müller cells
Methods qPCR, Western blot, CHIP, transfection, MTT assay, flow cytometry, luciferase reporter assay
Expression pattern down-regulated
Functional description miR-29b controled MIAT to regulate its expression and MIAT overexpression suppressed miR-29b.MIAT suppression reversed the effect induced by high glucose, however, miR-29b knockdown reversed the effects induced by MIAT suppression.
PubMed ID 28246353
Year 2017
Title Long non-coding RNA MIAT acts as a biomarker in diabetic retinopathy by absorbing miR-29b and regulating cell apoptosis.
Drug-related ncRNA NO

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