A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name hsa-miR-200b
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line serum
Methods luciferase reporter assay, qRT-PCR, Western blot, ADPase histochemical staining, immunohistochemistry
Expression pattern down-regulated
Functional description In comparison with the control group, the case group showed lower expression of miR-200b but higher expression of VEGFA mRNA. miR-200b might alleviate DR development by down-regulating its target gene VEGFA.
PubMed ID 28122882
Year 2017
Title Effects of miRNA-200b on the development of diabetic retinopathy by targeting VEGFA gene.
Drug-related ncRNA NO

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