A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name LSD1 siRNA
ncRNA Category siRNA
Disease name diabetic retinopathy (DR)
Species Bos taurus
Tissues/Cell_line bovine retinal endothelial cells (BRECs)
Methods siRNA transfection, CHIP assay, qPCR, Western blot
Expression pattern associated
Functional description Regulation of LSD1 by LSD1-siRNA ameliorated glucose-induced decrease in H3K4 methylation at Sod2, and prevented decrease in Sod2 gene expression.
PubMed ID 23221071
Year 2013
Title Epigenetic modification of Sod2 in the development of diabetic retinopathy and in the metabolic memory: role of histone methylation.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.