A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name CTGF siRNA
ncRNA Category siRNA
Disease name diabetic retinopathy (DR)
Species Rattus norvegicus
Tissues/Cell_line retinas
Methods siRNA injection, RT-PCR, Western blot, immunohistochemistry, TUNEL assay
Expression pattern associated
Functional description SiRNA-mediated inhibition of CTGF mRNA inhibited retinal VEGF and TGF-β(2) and also resulted in a significant decrease in apoptosis.
PubMed ID 20039857
Year 2010
Title The role of CTGF in the diabetic rat retina and its relationship with VEGF and TGF-β(2) , elucidated by treatment with CTGFsiRNA.
Drug-related ncRNA NO

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