A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name hsa-miR-145
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line human RPE cell line ARPE-19; human retinal microvascular endothelial cells (HRMECs)
Methods CCK-8 assay, apoptosis assay, ELISA, transfection, qRT-PCR, Western blot
Expression pattern up-regulated
Functional description Results demonstrated that BAI exhibited the protective effect against HG-induced cell injury by up-regulation of miR-145.
PubMed ID 30625293
Year 2019
Title Baicalin protects human retinal pigment epithelial cell lines against high glucose-induced cell injury by up-regulation of microRNA-145.
Drug-related ncRNA YES (Baicalin)

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