A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name GPR91 shRNA
ncRNA Category shRNA
Disease name diabetic retinopathy (DR)
Species Rattus norvegicus
Tissues/Cell_line retinas
Methods shRNA injection, immunofluorescence, qRT-PCR, Western blot, ELISA, luciferase reporter assay, CHIP assay
Expression pattern associated
Functional description Treatment with GPR91 shRNA attenuated the retinal avascular area, abnormal neovascularization and pericyte loss.
PubMed ID 28374767
Year 2017
Title Transcription factors regulate GPR91-mediated expression of VEGF in hypoxia-induced retinopathy.
Drug-related ncRNA NA

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