A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name Hottip
ncRNA Category lncRNA
Ensembl NA
Synonyms NA
Disease name diabetic retinopathy (DR)
Species Rattus norvegicus
Tissues/Cell_line retinas
Methods shRNA knockdown, qRT-PCR, Western blot
Expression pattern up-regulated
Functional description HOTTIP improves diabetic retinal microangiopathy through the p38-MAPK pathway. Down-regulation of HOTTIP can reduce the visual function decline and apoptosis of retinal cells caused by diabetes.
PubMed ID 29863235
Year 2018
Title LncRNA HOTTIP improves diabetic retinopathy by regulating the p38-MAPK pathway.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.