A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name MALAT1
ncRNA Category lncRNA
ID 378938
Ensembl ENSG00000251562
Synonyms HCN, LINC00047, MALAT-1, NCRNA00047, NEAT2, PRO1073, mascRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line human retinal endothelial cells (HRECs); vitreous humor
Methods siRNA transfection, RNA immunoprecipitation (RIP), Western blot, qRT-PCR, cell viability assay
Expression pattern up-regulated
Functional description Our findings collectively demonstrate the importance of MALAT1 in inflammation and epigenetic regulation in DR.
PubMed ID 29695738
Year 2018
Title MALAT1: An Epigenetic Regulator of Inflammation in Diabetic Retinopathy.
Drug-related ncRNA NO

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