A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name Miat
ncRNA Category lncRNA
ID 330166
Ensembl ENSMUSG00000097767
Synonyms A230057G18Rik, Rncr2, gomafu
Disease name diabetic retinopathy (DR)
Species Mus musculus
Tissues/Cell_line mouse Müller cells
Methods qPCR, Western blot, CHIP, transfection, MTT assay, flow cytometry, luciferase reporter assay
Expression pattern up-regulated
Functional description High glucose stimulation increased the cell apoptosis and decreased the cell activity, while MIAT suppression reversed the effect induced by high glucose, however, miR-29b knockdown reversed the effects induced by MIAT suppression.
PubMed ID 28246353
Year 2017
Title Long non-coding RNA MIAT acts as a biomarker in diabetic retinopathy by absorbing miR-29b and regulating cell apoptosis.
Drug-related ncRNA NO

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