A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name Dnmt1 siRNA
ncRNA Category siRNA
Disease name diabetic retinopathy (DR)
Species Mus musculus
Tissues/Cell_line retinas
Methods siRNA injection, chromatin Immunoprecipitation (ChIP), qRT-PCR
Expression pattern associated
Functional description In mouse retinal microvessels, Dnmt1-siRNA ameliorated diabetes-induced increase in Rac1 transcripts and activity, and decreased ROS levels.
PubMed ID 30347077
Year 2018
Title Epigenetics and Regulation of Oxidative Stress in Diabetic Retinopathy.
Drug-related ncRNA NO

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