A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name p66Shc siRNA
ncRNA Category siRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line human retinal endothelial cells (HRECs)
Methods siRNA transfection, qPCR, Western blot, immunofluorescence, chromatin immunoprecipitation (ChIP)
Expression pattern associated
Functional description P66shc-small interfering RNA (siRNA) inhibited glucose-induced Rac1 activation and mitochondrial damage.
PubMed ID 30105917
Year 2019
Title Adaptor Protein p66Shc: A Link Between Cytosolic and Mitochondrial Dysfunction in the Development of Diabetic Retinopathy.
Drug-related ncRNA NO

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