A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of choroidal neovascularization (CNV)
ncRNA name miR(5,B,7)
ncRNA Category miRNA
Disease name choroidal neovascularization (CNV)
Species Mus musculus
Tissues/Cell_line RPE and choroids
Methods immunostaining, Western blot, qPCR, RT-PCR
Expression pattern associated
Functional description A significant reduction in CNV was observed in a laser-induced CNV mouse model 57 days post-injection of the AAV5 particles conveying either anti-VEGFA miRNA and PEDF dual therapy or anti-VEGFA miRNA monotherapy.
PubMed ID 30825671
Year 2019
Title Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy.
Drug-related ncRNA NO

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