A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of choroidal neovascularization (CNV)
ncRNA name CD46 siRNA
ncRNA Category siRNA
Disease name choroidal neovascularization (CNV)
Species Homo sapiens
Tissues/Cell_line human RPE cell line ARPE-19
Methods immunohistochemistry, Western blot, siRNA transfection, ELISA
Expression pattern associated
Functional description CD46 knockdown increased release of VEGF on the apical and basal sides of ARPE-19 cells in culture by 1.3- (P = 0.012) and 1.2-fold (P = 0.017), respectively.
PubMed ID 26161984
Year 2015
Title Nitrite Modification of Extracellular Matrix Alters CD46 Expression and VEGF Release in Human Retinal Pigment Epithelium.
Drug-related ncRNA NO

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