A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of choroidal neovascularization (CNV)
ncRNA name TWIST1 siRNA
ncRNA Category siRNA
Disease name choroidal neovascularization (CNV)
Species Homo sapiens
Tissues/Cell_line human retinal microvascular endothelial cells (HRMECs)
Methods siRNA transfection, Western blot
Expression pattern associated
Functional description Knockdown of TWIST1 in endothelial cells led to dampened expression of vascular endothelial growth factor receptor 2 (VEGFR2) and decreased endothelial cell proliferation.
PubMed ID 25414194
Year 2014
Title Endothelial TWIST1 promotes pathological ocular angiogenesis.
Drug-related ncRNA NO

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