A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of choroidal neovascularization (CNV)
ncRNA name hsa-miR-342-5p
ncRNA Category miRNA
Disease name choroidal neovascularization (CNV)
Species Homo sapiens
Tissues/Cell_line human umbilical cord biopsies, primary human umbilical vein ECs (HUVECs)
Methods TUNEL assay, Western blot, RNA-seq, qRT-PCR, luciferase reporter assay, immunofluorescence
Expression pattern down-regulated
Functional description miR-342-5p acts as a multifunctional angiogenic repressor mediating the effects and interaction among angiogenic pathways.
PubMed ID 26857067
Year 2016
Title miR-342-5p Is a Notch Downstream Molecule and Regulates Multiple Angiogenic Pathways Including Notch, Vascular Endothelial Growth Factor and Transforming Growth Factor β Signaling.
Drug-related ncRNA NO

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